🔬 Statin guidelines change: new LDL-C goals and label update

The ACC/AHA released the 2026 Guideline, restoring explicit numeric LDL-C goals for very high-risk ASCVD patients to under 55 mg/dL. Concurrently, a 2026 CTT meta-analysis found no evidence that statins cause most listed adverse effects. This research analyzed data from over 150,000 patients across 23 double-blind statin trials. This dual change significantly alters treatment decisions regarding add-on therapy and patient counseling. Clinicians must now navigate tighter targets alongside reassessed safety profiles for these widely prescribed drugs.

💰 Mahavatar Narsimha dominates post-COVID box office

Mahavatar Narsimha became the most profitable film in the post-COVID Bollywood era. This mythological animation film was made in India with a modest budget of 15 crore. It earned a net collection of 247.96 crore, achieving a massive 1553.07% return on investment by almost 400 days. Despite big earnings, Ranveer Singh's Dhurandhar films failed to crack the top 5 due to their huge budgets. Saiyaara secured the fifth spot, showing that ROI matters more than sheer collection. 🎬

💰 Worst animated movie becomes a massive hit

Niu Lai, initially labeled as the worst animated film, has unexpectedly become a major box office success. The movie is from a mother-son duo and was released in China on August 5th. Despite starting with only RMB 7,700 in its first ten days, its earnings skyrocketed to over RMB 29 million. This massive profit comes from a shoestring budget of under $200, thanks to social media buzz. The film follows a timid calf learning courage in a mysterious dream. 🤩

🌟 Capricorn Horoscope: Social Life Brings Attention Today

Capricorn natives may see long-term desires coming true as Saturn supports tangible results. Relationships are bright, and if single, social circles could bring unexpected attention. Career progresses well due to disciplined planning and steady output, offering growth opportunities. Financially, income looks good through regular work, suggesting sensible savings are best. Overall health remains steady, but pacing is key amidst busy social and work commitments. 😌

🩺 Bloating: It's more than just feeling stuffed

Bloating is a very common symptom linked to various disorders of gut-brain interaction, yet there is no single FDA-approved drug for it. Gastroenterologist Dr Alicia Muratore is starting a six-episode series to dissect the science and myths around this issue. She clarifies that bloating, a subjective fullness, differs from visible abdominal distension. Alarm features, like weight loss or GI bleeding in women over 50, must be screened for before assuming a functional diagnosis. Next, the series will explore the five distinct mechanisms that cause bloating. 🧐

💇 GLP-1 weight loss side effect: Hair shedding reality

Unexpected hair shedding is becoming a talked-about side effect for patients using GLP-1 drugs. Research in 2026 links medications like semaglutide and tirzepatide to alopecia risk, especially with rapid weight loss. Studies show temporary hair thinning (telogen effluvium) affects a small segment of patients. The absolute risk is low, but the emotional impact for users is significant. Recovery can take six to nine months once the metabolic stress stabilizes. 😟

🎬 Prithviraj's Khalifa lands in Kerala's top 10 pre-sales

Prithviraj Sukumaran's movie Khalifa has started its theatrical run after an advance booking period. In Kerala, the film grossed 3.01 crore during its Onam pre-sales, which was recorded across 1,616 shows. Globally, the film's worldwide pre-sale collection has reached 6.4 crore as of Wednesday evening. The movie aims to surpass Aadujeevitham's opening to become Prithviraj's biggest solo lead debut. Mohanlal's cameo is a major highlight adding to the film's buzz. 🎬

🌌 Dune 3 aims for massive $100M+ opening weekend

Dune 3 is projected to hit over $100 million in its North American opening weekend. The film, starring Timothée Chalamet, is the final installment helmed by Denis Villeneuve. AMC CEO Adam Aron noted its pre-sales generated huge hype, surpassing Spider-Man: Brand New Day. This would mark a first for the franchise and the first high-end sci-fi film to cross that mark. The movie is set to release in North America on December 18. 🚀

🎬 Vishwanath And Sons close to Suriya's top 5

The Tamil romantic comedy Vishwanath and Sons has reached a net collection of 77.40 crore in India. This film, directed by Venky Atluri, is currently charting well against competition in the market. As of Day 6, it added 5.1 crore net, bringing its total to 77.40 crore across Tamil and Telugu versions. The film needs just 3.6 crore more to enter Suriya’s top 5 highest-grossing films. This recovery places it strongly towards hitting the 100 crore mark. 🎬

🩺 Double blood match boosts kidney transplant chances

NHS Blood and Transplant is rolling out a successful pilot trial for 'double matching' blood transfusions for kidney transplant recipients across the UK. This £1.37 million scheme will match blood for both red and white blood cells, aiming to lower transplant rejection risk. The new technique could prevent up to 100 annual rejections by reducing antibody-mediated rejection episodes. This is crucial because 38% of transplant patients develop HLA-specific antibodies after transfusions. The expanded rollout is expected to provide 4000 double-matched units nationwide each year. 🩺

🎬 DC on track to hit big Kollywood milestone

Lokesh Kanagaraj's debut film DC is maintaining a strong run at the box office despite reduced show counts. The Suriya starrer is currently at a net collection of 60.13 crore after 13 days, with overseas grossing 21.5 crore. The film is projected to surpass Thaai Kizhavi's lifetime collection during its third weekend. This places DC as the 4th highest-grossing Kollywood film of 2026. However, it will trail Jana Nayagan, Karuppu, and Vishwanath & Sons in the rankings.