𧬠Sperm DNA is rewriting itself way earlier than thought
Some genetic variation in human sperm appears to begin development earlier than scientists previously believed. Researchers from Wellcome Sanger Institute and the University of Cambridge found this while studying 15 sperm samples from 13 donors aged 24 to 74. They identified 7,143 crossovers and 2,382 non-crossover gene conversion events directly in the sperm DNA. This suggests a two-stage recombination model, where DNA repair activity precedes the specialized division of meiosis. Understanding this earlier activity offers new insights into how genetic diversity is generated and inherited.π¬