π¬ Scientists find how deadly fungus makes giant cells
Researchers at CCMB in Hyderabad uncovered the biological circuit enabling Cryptococcus neoformans to form Titan cells. This dangerous fungus, which spreads from lungs to the brain, was studied by Dr Sriram Varahan's team. The study revealed a link between glucose metabolism and calcium signalling, observed on May 15, 2024. This mechanism helps the fungus evade the immune system, which is a major issue globally. Future antifungal therapies could potentially target this specific cell-forming process. π¬