π¬ Pomegranate peel nanoparticles fight arthritis
Researchers developed chitosan nanoparticles loaded with punicalagin extract from pomegranate peels to treat arthritis. This study was conducted on 20 female Wistar rats with induced rheumatoid arthritis at institutions in Iran. The encapsulated treatment showed superior anti-inflammatory effects compared to punicalagin alone. It significantly reduced markers like RF, malondialdehyde, and the expression of TNF-Ξ± and CD20 genes. These findings suggest that nanoparticle encapsulation enhances the therapeutic outcomes for rheumatoid arthritis.