💇 GLP-1 weight loss side effect: Hair shedding reality

Unexpected hair shedding is becoming a talked-about side effect for patients using GLP-1 drugs. Research in 2026 links medications like semaglutide and tirzepatide to alopecia risk, especially with rapid weight loss. Studies show temporary hair thinning (telogen effluvium) affects a small segment of patients. The absolute risk is low, but the emotional impact for users is significant. Recovery can take six to nine months once the metabolic stress stabilizes. 😟

🎬 Prithviraj's Khalifa lands in Kerala's top 10 pre-sales

Prithviraj Sukumaran's movie Khalifa has started its theatrical run after an advance booking period. In Kerala, the film grossed 3.01 crore during its Onam pre-sales, which was recorded across 1,616 shows. Globally, the film's worldwide pre-sale collection has reached 6.4 crore as of Wednesday evening. The movie aims to surpass Aadujeevitham's opening to become Prithviraj's biggest solo lead debut. Mohanlal's cameo is a major highlight adding to the film's buzz. 🎬

🌌 Dune 3 aims for massive $100M+ opening weekend

Dune 3 is projected to hit over $100 million in its North American opening weekend. The film, starring Timothée Chalamet, is the final installment helmed by Denis Villeneuve. AMC CEO Adam Aron noted its pre-sales generated huge hype, surpassing Spider-Man: Brand New Day. This would mark a first for the franchise and the first high-end sci-fi film to cross that mark. The movie is set to release in North America on December 18. 🚀

🎬 Vishwanath And Sons close to Suriya's top 5

The Tamil romantic comedy Vishwanath and Sons has reached a net collection of 77.40 crore in India. This film, directed by Venky Atluri, is currently charting well against competition in the market. As of Day 6, it added 5.1 crore net, bringing its total to 77.40 crore across Tamil and Telugu versions. The film needs just 3.6 crore more to enter Suriya’s top 5 highest-grossing films. This recovery places it strongly towards hitting the 100 crore mark. 🎬

🩺 Double blood match boosts kidney transplant chances

NHS Blood and Transplant is rolling out a successful pilot trial for 'double matching' blood transfusions for kidney transplant recipients across the UK. This £1.37 million scheme will match blood for both red and white blood cells, aiming to lower transplant rejection risk. The new technique could prevent up to 100 annual rejections by reducing antibody-mediated rejection episodes. This is crucial because 38% of transplant patients develop HLA-specific antibodies after transfusions. The expanded rollout is expected to provide 4000 double-matched units nationwide each year. 🩺

🎬 DC on track to hit big Kollywood milestone

Lokesh Kanagaraj's debut film DC is maintaining a strong run at the box office despite reduced show counts. The Suriya starrer is currently at a net collection of 60.13 crore after 13 days, with overseas grossing 21.5 crore. The film is projected to surpass Thaai Kizhavi's lifetime collection during its third weekend. This places DC as the 4th highest-grossing Kollywood film of 2026. However, it will trail Jana Nayagan, Karuppu, and Vishwanath & Sons in the rankings.

🩺 Missing Cardiovascular Risk Factor: Lp(a)

Lipoprotein(a), or Lp(a), is a genetically determined cardiovascular risk factor often overlooked in primary care. This factor is independently linked to premature cardiovascular disease and aortic valve stenosis. Current guidelines suggest measuring Lp(a) at least once during adulthood for certain patients. Lifestyle changes offer minimal impact on Lp(a) levels, despite their overall importance. Measuring this factor allows doctors to better manage other modifiable heart risks. 🩺

💥 RDJ's Doctor Doom drives huge pre-sales for Avengers: Doomsday

Avengers: Doomsday is generating massive hype, largely due to Robert Downey Jr.'s portrayal of Doctor Doom. The film is set to clash with Dune 3, and its pre-sales are already performing incredibly well. As of now, the movie has crossed $35 million in pre-sales, with four months remaining until its release date. This achievement is historic because it surpasses any previous movie's pre-sale record in cinema history. The film is projected to earn over $100 million domestically if this momentum continues.

🏆 The Odyssey beats Deadpool & Wolverine globally

The Odyssey has achieved the title of all-time highest-grossing R-rated movie worldwide. The Christopher Nolan-helmed film surpassed Deadpool & Wolverine's global haul, according to an IGN report. The Odyssey has already crossed $1.34 billion worldwide since its July 17 release. This epic is also the first MCU film to receive an R-rated certificate. It continues to earn money with 70MM IMAX screenings running until September 16.

🔥 Coal still rules global power despite green push 🏭

Coal remains the top electricity generator globally, producing 10,974 TWh in 2026 according to the IEA. This dominance is particularly seen in China, where it supplied 55% of electricity in 2025, and India, at roughly 71%. The ongoing US-Iran war has unexpectedly boosted coal's competitiveness by driving up gas prices. While renewables are growing fast, combined wind and solar still lag coal by 44% in 2026. The IEA projects coal will remain the largest source through 2030 despite a slow annual decline.

🔬 New catalyst makes drug synthesis way easier

A novel organocatalytic reaction simplifies the creation of oligonucleotide drugs based on modified nucleic acid chains. Ming Shang and colleagues at Shanghai Jiao Tong University in China achieved this by replacing temporary molecular guides. The method was demonstrated across over 20 nucleoside combinations, successfully forming various phosphorus bonds. This approach offers a less expensive and scalable alternative to older methods that required bulky chiral auxiliaries. Ultimately, this research aims to better understand how phosphorus stereochemistry impacts drug performance. 🧬