🔬 FTO overexpression fights kidney cell damage in research
Overexpression of FTO was found to inhibit ferroptosis caused by OGD/R in mouse renal tubular epithelial cells. This research was conducted by various authors at Baoshan People’s Hospital. Key findings were documented on September 24, 2026, with significant markers increased in injury models. FTO activation works by boosting the NRF2/SLC7A11/GPX4 pathway, reducing cell injury. This suggests FTO could be a target for managing Acute Kidney Injury (AKI).