health π§ͺ COVID antivirals effectiveness is fading, research shows
New research suggests that COVID antivirals are not working as effectively as previously thought against the virus. In Australia, initial trials showed Paxlovid reduced severe illness by 89%, but newer studies paint a different picture. Two randomized controlled trials in vaccinated people showed no reduction in severe outcomes for either drug. A meta-analysis found Paxlovid was associated with a 40% reduction in hospitalisation, while Lagevrio's results were mixed. Given these findings, GPs should be consulted about antiviral use for at-risk groups. π