๐ง Brain immune cells offer new Alzheimer's clues
A new study mapped the brain's immune cells in Alzheimer's disease progression, identifying a protective cell subtype. Researchers at Mount Sinai analyzed over 830,000 myeloid-origin immune cells from 1,607 donors. The study revealed a disease-associated microglia that clears harmful material, supported by molecular pathways like TREM2. These findings offer new directions for developing therapies that boost the brain's defense mechanisms. This research provides the most detailed reference on immune cell changes across the lifespan.