❤️ Big updates in heart health and medicine

A new Fifth Universal Definition categorizes myocardial infarction into primary, secondary, or procedure-related types. Eli Lilly got FDA approval for tirzepatide to lower heart attack risk in Type 2 diabetes patients. In the AIR-STEMI trial, revascularization guided by functional angiography showed fewer major cardiovascular events. Inclisiran proved safer and more effective than bempedoic acid in lowering LDL cholesterol, per the VICTORION-Challenge trial. Allegations of misconduct surfaced against a former ESC president over conflicts of interest. 🩺

🎬 Bollywood's August box office dipped, but two films crushed it

Bollywood's total net collection fell by 17% in August 2026 compared to July's haul. Awarapan 2 and Hanuman Ansh emerged as major successes during this month in India. These films contributed 154 crore and 45.63 crore net, respectively, out of the total 255.29 crore. While Batwara 1947 disappointed, the success ratio improved with two hits this month. The next major releases, Mirzapur The Movie and Haiwaan, will be tracked in September.

🎬 Daayra trailer hints at big box office debut

The crime thriller Daayra, starring Kareena Kapoor Khan and Prithviraj Sukumaran, shows strong potential based on its trailer. Directed by Meghna Gulzar, the film is positioned to outperform Deepika Padukone’s Chhapaak on its opening day. Chhapaak had opened at 4.77 crore, which is Gulzar's third-highest career opener. Given the trailer's reception, Daayra could aim to surpass Gulzar's previous best openings. However, releases like Kunal Kemmu’s Vibe might limit its initial run.

🕸️ Spider-Man: Brand New Day hits top 3 box office

Spider-Man: Brand New Day officially joined the all-time top 3 highest-grossing films worldwide on Monday. This massive superhero movie, starring Tom Holland, achieved this milestone after a strong run. The film has grossed over $2.33 billion globally, surpassing Avatar: The Way of Water. This is noted as the biggest-ever solo superhero movie, marking a shift in Disney's top-tier film list. The movie, released on July 31, is tracking to earn between $2.5 billion and $2.7 billion in its original run.

🎬 Haiwaan needs 3.07 Cr to hit top 3 crime thriller spot

Akshay Kumar and Saif Ali Khan's crime thriller, Haiwaan, is set to release soon after its excitement built up. The film stars Saif as a visually impaired protagonist and Akshay as the antagonist, directed by Priyadarshan. To secure the third spot among post-COVID crime thriller openers, the movie needs an opening collection of 3.07 crore on Day 1. Currently, Chup: Revenge Of The Artist holds this third spot with 3.06 crore. The film aims to challenge Raid 2 and Drishyam 2 for the top two openings. 🎬

🕷️ Spider-Man nears Avatar's Chinese box office mark

Spider-Man: Brand New Day is steadily climbing the Chinese box office rankings, getting closer to Avatar: The Way of Water’s total. The Marvel film currently stands at $225.7 million in China, while Avatar: The Way of Water earned an estimated $246 million there. In its fifth weekend, Spider-Man collected $2.9 million, securing a spot in the top five. This performance makes it the biggest Hollywood earner of this year in mainland China. The movie continues its global success, with Tom Holland becoming the third-highest-grossing actor of all time. 🕷️

🔬 Prostate cancer checkup: what's the latest?

The approach to prostate cancer diagnosis is changing fast with new tech like mpMRI and targeted biopsies. PSA remains the initial screening tool, but it needs context with age, symptoms, and family history. Routine PSA screening isn't advised for asymptomatic men over 70 due to potential harms. MRI-ultrasound fusion biopsy is preferred over TRUS biopsy when lesions look suspicious on mpMRI. PSMA PET/CT is key for finding cancer recurrence after local treatment. 🔬

🔬 China makes longest single-metal atom chains ever

Researchers in China successfully created the longest single-metal-atom chains to date using copper. The scientists achieved this by subjecting a copper phthalocyanine crystal to high pressure, specifically 21.5GPa. These resulting chains stretched over 4000 atoms long, with electrical conductivity coming from the internal carbon layer. The team now plans to test this high-pressure strategy on other metal-phthalocyanine structures like cobalt and nickel. Experts remain cautious about the scalability of this complex, high-pressure synthesis method. 🔬

🔬 New RNA approach tackles CF mutations

Researchers developed chemically engineered suppressor tRNAs packaged in lung-targeted lipid nanoparticles to treat nonsense mutation cystic fibrosis. This work was conducted by Jingan Chen and colleagues in preclinical models, including mouse models and patient-derived organoids. The study demonstrated that the treatment successfully restored functional CFTR protein production in these various cellular systems. This method aims to correct protein production at the mutation site instead of editing the underlying DNA. However, further research is needed regarding the safety of repeated doses due to observed inflammation.

🩺 Late bleeding after heart procedure linked to higher death risk

Ischaemic and bleeding complications during Percutaneous Coronary Intervention (PCI) increased the risk of in-hospital death. Researchers analyzed data from 54,599 patients in France between 2014 and 2020. While in-hospital complications saw a 2.1% mortality rate, late bleeding after 24 weeks showed a stronger link to death. This suggests that prolonged dual antiplatelet therapy needs careful re-evaluation for patients. The study highlights that late bleeding complications might be riskier than late ischaemic ones. 🩺

🎬 Awarapan 2 close to beating Ajay Devgn's hit

Awarapan 2 is showing signs of box office fatigue, with its worldwide gross standing at 214.8 crore after 18 days. The film, starring Emraan Hashmi, Disha Patani, and Shabana Azmi, earned 181.74 crore in India and 33.06 crore overseas. It currently needs just 1.39 crore more to surpass Ajay Devgn's Shaitaan, which is projected in the next few days. This success places Awarapan 2 as the 5th highest-grossing Bollywood film of 2026 so far. The movie's run will conclude above Welcome To The Jungle's collection. 🎬