🔬 BCG plus immunotherapy cuts TB relapse risk

Researchers found that combining BCG vaccination with recombinant APRIL significantly lowered tuberculosis relapse rates in preclinical studies. This study, led by scientists at the Hackensack Meridian Center for Discovery and Innovation, investigated B-cell targeting to boost TB protection. The combined treatment resulted in a 26 percent relapse rate, versus 60 percent for BCG alone. This suggests B cells are key to strengthening long-term immunity against TB recurrence. Further human trials are needed to confirm this promising therapeutic strategy. 🔬

🎬 Soori's Mandaadi hits 100 crore mark

Soori's sports drama Mandaadi has achieved a major box office milestone, crossing the 100 crore worldwide mark. The film was released in Tamil and is starring Soori, Suhas, and Mahima Nambiar. As of Day 11, the net domestic total is 75.55 crore, while overseas collections added 15.4 crore. This performance puts the film on track to secure a hit verdict from its 50 crore budget. It has also surpassed the lifetime collection of DC at the domestic box office.

🔬 Europe's advanced therapies face new regulatory challenges

Professor Jacob George discussed the evolving regulatory landscape for Advanced Therapy Medicinal Products (ATMPs) at Advanced Therapies Europe in Barcelona. He explained that ATMPs, like cell & gene therapies, pose challenges due to their patient-specific and complex nature. Key points included the need for proportionate regulation and regulatory agility to support innovation. International collaboration is crucial to reduce costs and ensure timely patient access to these transformative treatments. Frameworks must evolve alongside the science to maintain both safety and high-quality standards.

🔬 ED linked to higher glaucoma risk in men

Men diagnosed with or treated for erectile dysfunction (ED) showed increased odds of developing primary open-angle glaucoma (POAG). Researchers conducted a prospective nested case-control study using two UK databases between 2005 and 2022. The study found ED was associated with higher odds in both the Gold dataset (aOR 1.23) and Aurum dataset (aOR 1.12). This suggests ED might reflect systemic vascular issues relevant to early glaucoma detection. Further research should explore these vascular biomarkers for better screening methods. 🧐

🏥 JK Govt rules out OPS for later regularised teachers

The Jammu and Kashmir government has clarified its stance on pension benefits for ReT teachers following an MLA's query. The government ruled out the Old Pension Scheme (OPS) for teachers regularised after January 1, 2010, in Srinagar. However, it confirmed that the initial five years of pre-regularisation service will count for retirement benefits, citing Cabinet Decision No. 115/09/2014. This decision is based on the fact that those regularised before 01.01.2010 fall under OPS, while others are under the NPS. The government also confirmed periodic health infrastructure assessments in the Budgam constituency. 🏥

🔬 Obesity's Immune Changes Might Be Reversible

Obesity is known to alter the immune system, affecting nearly 1 in 5 adults in Germany by increasing proinflammatory monocytes. Ulf Wagner reported that these obesity-related monocyte changes can largely return to normal after bariatric surgery and significant weight loss. A study of 111 obese participants showed they lost an average of 44.5 kg within one year after surgery. This finding suggests a common mechanism linking obesity inflammation and rheumatoid arthritis, potentially reducing cancer risk. Future research will test if RA anti-inflammatory drugs can also improve metabolism in obese patients. 🔬

🇮🇳 India's Asian Games Journey: Day 2 Updates

India's participation in the Asian Games continued with action unfolding on Day 2. The events are taking place in Aichi-Nagoya. Key competitions are scheduled for September 21, 2026. This phase builds upon earlier performances in the tournament. Fans can keep up with the latest updates as the games progress. 🇮🇳

🚨 Man Kills Brother-in-Law for Sister's Murder

A man allegedly murdered his sister's husband as an act of revenge for her own murder. The incident occurred in an unspecified location, involving the family members. The plot reportedly started after the brother-in-law was granted bail. This action was taken in retaliation for the initial crime committed against the sister. Authorities are currently investigating the details of this violent sequence of events. 🚨

🥇 Harmeet dominates as India beats Pakistan in table tennis

India secured an early advantage against Pakistan in table tennis on Day 3 of the Asian Games 2026. Harmeet Desai was the star player, completely dominating the matches against Muhammad Khan. He won the first game 11-4, followed by another win 11-3, and closed it out with 11-5. This strong performance helps India's overall campaign at the Aichi-Nagoya games. More updates on the Indian team's journey are expected throughout the day. 🇮🇳

😠 BJD pressures govt to scrap MMDR amendment

Former CM Naveen Patnaik urged CM Mohan Charan Majhi to call a special assembly session to repeal the MMDR Amendment Act 2026. This was addressed to Mr. Majhi ahead of the Orissa Legislative Assembly session starting on September 22. Patnaik stated the amendment strips Odisha of its constitutional right to tax mineral wealth, causing potential financial losses. He noted the Supreme Court previously upheld Odisha's right, securing crores in dues and Rs. 12,000 crore annual revenue. A resolution would reaffirm these rights and protect Odisha's interests. 😠

🥇 India dominates table tennis, swimming updates

India secured a 3-0 victory against Pakistan in table tennis, moving into the women's team quarter-finals. This success happened in the Asian Games 2026 held in Aichi-Nagoya, Japan. The Indian women's team topped Group F with three wins from three matches. Meanwhile, Akash Mani and Heer Gitesh Shah missed the men's 50m freestyle final after finishing 26th and 28th. Srihari Nataraj qualified for the men's 50m backstroke final with a time of 25.37s. 🏊